Twin Health Secures $53M for AI-Based Metabolic Health Platform

Twin Health, a Mountain View-based company developing AI digital twin technology for metabolic health, announced a $53 million investment led by Maj Invest of Denmark to accelerate its expansion among health plans and Fortune 500 clients in retail, healthcare, financial services, technology and manufacturing sectors. The funding comes as 38.4 million people have diabetes (11.6% of the U.S. population) and 40.3% of adults during August 2021–August 2023 have obesity, according to CDC data.

Key Points

  • The company’s AI digital twin technology creates personalized metabolic models using data from smart devices, lab results, and meal logs to provide individualized guidance on nutrition, activity, and sleep patterns. The platform aims to address diabetes and weight loss without relying on high-cost medications.
  • Twin Health announced results from a study published in the New England Journal of Medicine Catalyst indicating its approach can be effective for diabetes treatment and weight loss.
  • The platform operates on a performance-based pricing model where clients only pay when members achieve specific clinical outcomes such as A1C reduction or weight loss.
  • Twin Health’s approach combines AI technology with human care teams to provide what it describes as continuous, 24/7 guidance. The system is designed to help members transition off medications, including GLP-1s, over time.
  • The funding will support expansion among employers in retail, healthcare, financial services, technology, and manufacturing sectors. The company currently serves millions of eligible lives across its customer base.
  • Other innovative competitors in the digital metabolic health space include Virta Health, which offers nutrition-based diabetes management programs, and companies like Ciba Health and Fitterfly.

Twin Health offers employers and health plans a performance-based metabolic health service that combines AI technology with human coaching, aiming to help members improve diabetes and weight outcomes while reducing medication use.

The Data

  • Twin Health reports achieving $8,000+ in annualized savings per member through reduced medication reliance and lower medical utilization.
  • The company states it maintains over 90% retention rates with under 1% voluntary churn.
  • Clinical results have been published in peer-reviewed journals and publications from the American Heart Association, American Diabetes Association, and American College of Cardiology.
  • The platform uses thousands of data points across biomarkers, behaviors, and preferences to create each member’s digital twin model.
  • According to a 2024 KFF analysis, only 1% of ACA Marketplace prescription drug plans cover Wegovy for weight loss, while GLP-1 medications can cost $936-$1,349 per month without insurance.
  • Data from healthcare analytics firm IQVIA shows health plans denied coverage for 62% of GLP-1 prescriptions for obesity in 2024, with 53% of prescriptions filled through cash payments.

Industry Context

Diabetes and obesity are among the world’s biggest health challenges. For decades, we have invested in cutting-edge solutions to address the epidemic of metabolic disease. Twin Health represents a paradigm shift in diabetes and obesity care – one that is precise to each individual and scalable for employers and health plans.

Jeppe Christianson, CEO of Maj Invest

The platform addresses what the company describes as failures in traditional metabolic health solutions that rely heavily on medications and extreme diets. Twin Health’s approach involves creating a real-time AI model for each member that reflects their individual metabolism and habits across nutrition, sleep, and physical activity. The technology provides personalized meal insights showing how specific foods impact an individual’s metabolism, with the stated goal of addressing root causes rather than managing symptoms.

The company positions itself within the growing market demand for what it calls “responsible GLP-1 strategies,” offering to identify eligible members for appropriate GLP-1 use while providing personalized pathways to reduce long-term medication dependence. Twin Health’s performance-based pricing model means employers and health plans pay only when clinical milestones are achieved.